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This variant 7 lacks multiple 3′ coding exons and contains an alternate 3′ terminal exon compared to variant alpha2. The encoded isoform 7 is much shorter than isoform alpha2. This variant beta1 results from the use of an alternate promoter, referred to 4158bp beta.
It contains an alternate 5′ terminal exon and lacks most of the 5′ exons and another exon in the 3′ region compared to variant alpha2.
(PDF) TC4518BP Datasheet download
The resulting isoform beta1 is shorter with a distinct N-terminus lacking the EGF-like domain and containing fewer laminin G domains compared to isoform alpha2. Datadheet variant alpha2 results from the use of the 5′-most promoter, referred to as alpha.
It represents the longest transcript that encodes the longest isoform alpha2 of the representative RefSeq variants. This isoform contains EGF-like, several laminin G, and syndecan domains. This variant 8 lacks multiple 3′ coding exons and contains an alternate 3′ exon structure compared to variant alpha2.
The encoded isoform 8 is much shorter than isoform alpha2 and has a distinct C-terminus. This variant alpha1 results from the use of the 5′-most promoter, referred to as alpha.
NRXN1 Human cDNA/ORF Clones
datashdet It lacks two in-frame exons and uses an alternate in-frame donor splice site at an internal exon compared to variant alpha2. The resulting isoform alpha1 is shorter missing a few internal protein segments compared to isoform alpha2.
This variant gamma1 results from the use of an alternate promoter, referred to as gamma. It contains an alternate 5′ terminal exon and lacks all the exons, except the last two 3′ terminal exons, compared to variant alpha2.
HEFBP, BG-ELECTRONICS HEFBP, BP, HEF, CDBP, CD, MC, LC, DM
Hence, the encoded isoform gamma1 is considerably shorter with a distinct N-terminus lacking the EGF-like and laminin G domains, and containing only the syndecan domain compared to isoform alpha2.
This variant 6 lacks multiple 3′ coding exons and contains an alternate 3′ terminal exon compared to variant alpha2. The encoded isoform 6 is much shorter than isoform alpha2. This variant 9 lacks multiple datashert coding exons datasheer contains an alternate 3′ terminal exon compared to variant alpha2. The encoded isoform 9 is much shorter than isoform alpha2 and has a distinct C-terminus.
This variant gamma2 results from the use of an alternate promoter, referred to as gamma. It contains an alternate 5′ terminal exon and lacks all the exons, except the last two 3′ terminal exons the penultimate exon uses an alternate in-frame donor splice sitecompared to variant alpha2.
Hence, the encoded isoform gamma2 is considerably shorter with a distinct N-terminus lacking the EGF-like and laminin G domains, and containing only the syndecan domain compared to isoform alpha2. Such clones are the best for detection and purification of the transgene using anti-FLAG or anti-His antibodies.