La cloroquina y la artritis reumatoide. SUMARIO. Sesenta y seis enfermos con artritis reumatoide activa fueron asignados al azar en nuimeros casi iguales al. Describimos el caso de una mujer de 60 años diagnosticada de artritis reumatoide hace 8 años y tratada desde entonces con cloroquina, que presentó signos. artritis reumatoidea (AR) hacen necesario una actualización regular de las guías de práctica clínica similares o mejores que los AINEs o la cloroquina
| Author: | Brasho Nikoshura |
| Country: | Turkey |
| Language: | English (Spanish) |
| Genre: | Education |
| Published (Last): | 8 January 2009 |
| Pages: | 422 |
| PDF File Size: | 7.47 Mb |
| ePub File Size: | 13.13 Mb |
| ISBN: | 334-4-16296-969-3 |
| Downloads: | 62607 |
| Price: | Free* [*Free Regsitration Required] |
| Uploader: | Zulkigul |
Antimalarials are long-standing drugs that have been used since the nineteenth century for the treatment of skin rashes and lesions in lupus and rheumatoid arthritis.
In recent decades, their use in these disorders has been consolidated, and new mechanisms of action have been incorporated, broadening the therapeutic perspectives of these drugs.
Antimalarials are the treatment of choice in mild and moderate manifestations of systemic lupus erythematosus and are established as part of combined therapy in rheumatoid arthritis.
They have been shown to have beneficial effects on atherosclerosis, as well as a possible role in the early treatment of antiphospholipid cliroquina. This review aims to provide an update on the use of these drugs in rheumatology and to discuss their toxicity profile.
Read this article in English.
Hospital Universitario Puerta de Hierro. This review aims to provide an update on the use of these drugs in rheumatology and to discuss their toxicity profile. Treatment of lupus erythematosus with mepacrine. Lancet, 2pp. Lupus, 5pp. Is there a role for quinacrina Rematoide in the new millennium. Lupus, 9pp. The benefit ofcombining hydroxychloroquine with quinacrine in the treatment of SLE patients. Further observations on the use of 4-aminoquinoline compounds in patients with rheumatoid arthritis related diseases.
Cleve Clin Q, 25pp.
Hidroxicloroquina
Pharmacokinetics of hydroxychloroquine and chloroquine during treatment of rheumatic diseases. Hydroxychloroquine concentration-response relationships in patients with rheumatoid arthritis. Arthritis Rheum, 46pp. Antimalarial drug induced decrease in creatinine clearance. J Rheumatol, 22pp.
Arch Ophthalmol, 70pp. Liver enzyme levels in artritis patirnts treated with long-term bolus methotrexate. Arthritis Rheum, 35pp. Patients with cutaneous lupus erythematosus who smoke are less responsive to antimalarial treatment.
J Am Acad Dermatol, 42pp. Effect of weak bases on the arritis pH in mouse peritoneal macrophages. J Cell Biol, 90pp. Mechanism of action of hydroxychloroquine as an antirheumatic drug. Sem Arthritis Rheum, 23pp. Antimalarial drugs in the treatment of rheumatological diseases. J Rheumatol, 36pp. Gen Pharmac, 30pp. Hydroxychloroquine in polymorphic light eruption: Brit J Dermatol,pp.
Antimalarials in cutaneous lupus erythematosus: Agtritis, 11pp. Lupus, 7pp. Influence of acute injection of chloroquine on the biliary secretion of lipids and lysosomal enzyme on rats.
Lipids, 19pp. Inhibition of ptoteolytic degradation of low density lipoprotein in human fibroblasts by chloroquine, concanavalin A and Triton WR J Biol Chem,pp. Chloroquine inhibits cyclization of squaleneoxide to lanosterol in mammalians cells.
Van der Moolen, M.
Lipids, 16pp. Serum lipoprotein inactive rheumatoid arthritis and other chronic inflammatory arthritides. Effects of anti-inflammatory and disease-modifying drug treatment.
Arch Intern Med,pp. Cholesterol-lowering effect of hydroxychloroquine in patients with rheumatic disease: Am J Med, 89pp. Hydroxychloroquine has nosignificant effect on lipids and apolipo proteins in Chinese systemic lupus erythematosus patients with mild or inactive disease.
The lipid, lipoprotein, and apolipoprotein effects of hydroxychloroquine in patients with systemic lupus erythematosus. J Rheumatol, 20pp. Effect of prednisone and hydroxychloroquine on coronary artery disease risk factors in systemic lupuserythematosus: Am J Med, 96pp. Hydroxychloroquine effects on lipoprotein profiles the HELP trial: J Clin Rheumatol, 3pp. Effect of disease modifying agents on the lipid profiles of patients with rheumatoid arthritis.
Ann Rheum Dis, 56pp. The cholesterol lowering effect of antimal arial drugs is enhanced in patients with lupus taking corticosteroid drugs. J Rheumatol, 26pp. Effect ofantimal arial agents on the fasting lipid profile in systemic lupus erythematosus. Rheumatol, 27pp. Longterm beneficial effect of choloroquine diphosphateon lipoprotein profile in lupus patients with and without steroidtherapy. J Rheumatol, 28pp. Hypoglycemia and antimal arial drugs: BMJ,pp. Hydroxychloroquine in decompensated treatment-refractory noninsulin- dependent diabetes mellitus.
A new job for an old drug?.
Ann Intern Med,pp. Hydroxychloroquine use in the Baltimore lupus cohort: Hypoglycemia induced by hydroxychloroquinein a type II diabetic treated for polyarthritis. Hydroxychloroquine and postoperative thromboembolism after total hip replacement. Am J Med, 85pp.
Prevention of post-operative deep venous thrombosis and pulmonary embolism. BMJ, 1pp.
Prevention of postoperative deep venous trombosis in artritiw by orally administered hydroxychloroquine sulfate. BMJ, 3pp. Hydroxychloroquine sulfate in prevention of thromboembolic phenomena in surgical patients. Am Surgeon, 41pp.
Hidroxicloroquina: MedlinePlus medicinas
Hydroxychloroquine sulphate in prevention of deep venous thrombosis following of the hip, pelvis, or thoracolumbar spine. J Bone Joint Surg Am, 58pp. Prevention of venous thromboembolism by administration of hydroxychloroquine. Failure of orally administered hydroxychloroquine sulphate to prevent venous thromboembolism following elective clorlquina operations.
J Bone Joint Surg Am, 59pp. Prophylaxis of deep venous trombosis by hydroxychloroquine sulfate and heparin. Surg Gynecol Obstet,pp. Clinical and experimental evaluation of the thromboprophylactic effect of hydroxychloroquine sulfate after total hip replacement. Haemostasis, rreumatoidepp. Med Trop, 50pp. Chloroquine inhibits atimulatedplatelets at the arachidonic acid pathway.
Thromb Res, 77pp. JAMA,pp. Hydroxychloroquine reverses thrombogenic properties of antiphospholipid antibodies in mice. Circulation, 96pp. Does hydroxychloroquine sulfate prevent clot formation in systemic lupus erythematosus?. Arthritis Rheum, aryritispp. The relevance of antimalarial theraphy with regard to thrombosis, hypercholesterolemia and cytokines in SLE. Lupus, 2pp.